Segmental Hyperhidrosis as a Manifestation of Spinal and Paraspinal Disease

Abstract

ABSTRACT:Background:Segmental hyperhidrosis is an uncommon finding which is usually associated with irritation or infiltration of pre-ganglionic sympathetic fibres or the sympathetic chain.Methods:We report two cases of segmental hyperhidrosis with striking clinical features.Results:In one case, a mesothelioma produced ipsilateral simultaneous underactivity and overactivity of sympathetic outflow and in the other case a thoracic central disc herniation was probably responsible for a band of sweating which clearly extended beyond the segmental level of injury.Conclusion:Segmental hyperhidrosis should trigger a search for structural disease in the spinal and paraspinal region.