A genetic dissection of the retinoid signalling pathway in the mouse-Reference-Cited by-同舟云学术

A genetic dissection of the retinoid signalling pathway in the mouse

Published:1999-08 Issue:3 Volume:58 Page:609-613
ISSN:0029-6651
Container-title:Proceedings of the Nutrition Society
language:en
Short-container-title:Proc. Nutr. Soc.

Author:

Mark Manuel,Ghyselinck Norbert B.,Wendling Olivia,Dupé Valérie,Mascrez Bénédicte,Kastner Philippe,Chambon Pierre

Abstract

To determine the functions of retinoic acid receptors RAR and RXR, we have systematically knocked-out their genes by homologous recombination in the embryonic stem cells and generated null-mutant mice. This approach has allowed us to perform a genetic dissection of the retinoic acid signalling pathway.

Publisher

Cambridge University Press (CUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference33 articles.

1. Contribution of retinoic acid receptor β isoforms to the formation of the conotruncal septum of the embryonic heart

2. In vivo functional analysis of the. Hoxa-13′ retinoic acid response element (3>RARE);Dupé;Development,1997

3. Roles of retinoic acid receptors and of. Hox genes in the patterning of the teeth and of the jaw skeleton;Mark;International Journal of Developmental Biology,1995

4. Limited specificity and large overlap of the functions of the mouse RARγ1 and RARγ2 isoforms

5. An analysis of the syndrome of malformations induced by maternal vitamin a deficiency. Effects of restoration of vitamin a at various times during gestation

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