Author:
van Diermen Linda,Walther Sebastian,Cools Olivia,Fransen Erik,Birkenhäger Tom K.,Sabbe Bernard C.G.,Schrijvers Didier
Abstract
AbstractObjectiveTo explore the correlations between observer ratings and instrumental parameters across domains of psychomotor functioning in depression.MethodIn total, 73 patients with major depressive disorder underwent extensive psychomotor and clinical testing. Psychomotor functioning was assessed with (i) an observer-rated scale (the CORE measure) and also objectively with (ii) 24-h actigraphy, and (iii) a fine motor drawing task.ResultsObserver ratings of retardation correlated with instrumental assessments of fine and gross motor functioning. In contrast, observer ratings of agitation did not correlate with observer ratings of retardation or with the instrumental measures. These associations were partly influenced by age and, to a lesser extent, by depression severity.ConclusionPsychomotor disturbance is a complex concept with different manifestations in depressed patients. Although observer ratings of retardation correspond well with instrumental measures of the motor domains, objective measurement of agitation and other aspects of psychomotor disturbance require further research.
Publisher
Cambridge University Press (CUP)
Subject
Biological Psychiatry,Psychiatry and Mental health
Cited by
9 articles.
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