Abstract
The formula H′C = 1 − CDZ/CMZ is suggested as a better summary of twin concordance data than the familiar Holzinger concordance formula, HC = (CMZ − CDZ)/ (1 − CDZ). The new formula better estimates degree of genetic determination, G, as calculated from a threshold model, but never exceeds unity, as G sometimes does. For high concordance rates, if CMZ + CDZ > 1, HC, may be more useful than either G or H′C.
Publisher
Cambridge University Press (CUP)
Reference2 articles.
1. The relative effect of nature and nurture influences on twin differences.
2. Concordance in twins: Methods and interpretation;Smith;Am J Hum Genet,1974
Cited by
8 articles.
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