Author:
Bomsel-Helmreich Ondine,Papiernik-Berkhauer Emile
Abstract
Aiming to show that delayed ovulation may induce MZ twinning, follicular maturation was induced in the rabbit by a small quantity of Pregnant Mare Serum Gonadotropin (16 UI four times): coitus, which induces ovulation in the rabbit, was delayed 60 hours after the last injection. From the 387 blastocysts obtained after this treatment, 6 (7.5%) were pairs of MZ twins, twinning being otherwise exceptional in the rabbit. Other anomalies were shown by the embryos, apparently related to a deficient quality of the eggs: high embryonic mortality (62% vs. 27% in controls) and chromosomal anomalies (20%) such as trisomies, triploidies, and chimaeras. The relation between MZ twinning, chromosomal anomalies, and embryonic mortality induced by delayed ovulation, could be connected and related to the poor perinatal conditions frequently observed in human MZ twins.
Publisher
Cambridge University Press (CUP)
Reference6 articles.
1. Turner's syndrome, twinning and an unusual variant of glucoses-phosphate dehydrogenase;Nance;Am. J. Hum. Genet.,1964
2. Over-ripeness and the mammalian ova. III. Fetal development at midgestation and at term;Butcher;Fertil. Steril.,1969
3. Monozygotic twins with the Turner syndrome
4. Monozygotic hetero-caryotic twinning. Proc. 1st Int. Congr. Twin Studies, Rome;Aurias;Acta Genet. Med. Gemellol. (Roma),1974
Cited by
31 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献