Ricerche sulla familiarità del carcinoma ovarico

Abstract

SUMMARYThe Autors have begun a genetic research on the ovarian cancer. In this first part of the work:1. it has been defined the group of the “ primary cases ” in which have been included 74 cases of solid carcinoma, 108 cases of cystic carcinoma and 93 cases of unclassified malignant tumor of the ovary.2. it has been studied the age of appearance and the age incidence variation of the ovarian cancer, and it has been found that:a) the mean age of appearance is 51,15 ± 0,64 years, but it lowers to 48,94 ± 0,68 years for the solid carcinoma and rises to 52,36 ± 0,90 years for the cystic carcinoma;b) the period of the greatest frequency of the disease is between 40-60 years of age, followed by a sharp decrease over age 65;3. it has been analysed the fertility of the patients, and it has ben recorded a decrease of the mean fertility up to 29% as compared to the general population;4. it has been mentioned the importance of the hormonal factor as a problable condition for the development of the ovarian cancer, that nevertheless calls for other — likely idiotypic — factors.