La Complexe Contribution du Génotype à la Prédisposition Morbide

Abstract

SUMMARYThe Author deals with the problem of morbid disposition from the genetic standpoint. He further reports and discusses the results obtained by studying 447 pairs of tuberculous brothers, as far as the age of onset, the clinical form and the localization of the tubercular process are concerned.Data are also reported concerning the morbidity of silicosis among 683 Sardinian mineworkers, especially concerning its frequency in the families of both affected and healthy propositi, for a total amount of 9,127 individuals examined. The results are also shown of a wide survey carried out on 293 single-born and 2,474 twins, concerning the following allergic diseases: eczema, asthma, urticaria and hay-fever. The possible mechanism of inheritance of morbid disposition is also discussed.