Concordance in a Twin Population Model-Reference-Cited by-同舟云学术

Concordance in a Twin Population Model

Published:1970-10 Issue:4 Volume:19 Page:584-590
ISSN:1120-9623
Container-title:Acta geneticae medicae et gemellologiae
language:en
Short-container-title:Acta genet. med. gemellol.

Author:

Selvin Steve

Abstract

SummaryA twin population model is proposed, and two different definitions of the rate of concordance are investigated within the context of this model. It is found that the statistic formed from the ratio of the number of affected twins that come from concordant pairs to all affected twins has certain advantages over the traditional definition of the rate of concordance. This twin population model is extended to nontruncated sample of twins. The parameters of this situation are estimated. Finally, it is shown how these parameters relate to the two usual estimates of the proportion of DZ. twins in a twin population, and the efficiency of these methods is computed.

Publisher

Cambridge University Press (CUP)

Reference11 articles.

1. Some methods of estimating the inbreeding coefficient;Li;Amer. J. Hum. Genet.,1953

2. Twinning in pedigrees;Waterhouse;Brit. J. Med.,1950

3. The estimation of the frequency of recessive conditions in man;Haldane;Ann. Eng.,1938

4. Systems of inbreeding I-IV;Wright;Genetics,1921

5. A classification of methods of ascertainment and analysis in estimating the frequency of recessives in man;Bailey;Ann. Hum. Genet.,1952

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Twin Azygotic Test for the Study of Hereditary Qualitative Traits in Twin Populations;Acta geneticae medicae et gemellologiae: twin research;1979-01

2. Twin Concordance. A More General Model;Acta geneticae medicae et gemellologiae: twin research;1979-01

3. Scope and Methodology of Twin Studies;Acta geneticae medicae et gemellologiae;1976-01

4. Multiple Pregnancy;New England Journal of Medicine;1973-06-21