Reactions and antibody response to live influenza vaccine prepared from the Iksha (A2) strain. (A report to the Medical Research Council by their Committee on Influenza and other Respiratory Virus Vaccines)

Author:

Beare A. S.,Tyreell D. A. J.,McDonald J. C.,Pollock T. M.,Taylor C. E. D.,Howells C. H. L.,Tyler L. E.

Abstract

Two field trials of A 2 live influenza vaccine (Iksha) are described; the clinical reactions and antibody response in three earlier trials are compared.The antibody response in the last two trials was unsatisfactory and was inferior to that observed in the earlier investigations. This reduction in response was probably due to an alteration in the virus during further passage.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,Immunology

Reference13 articles.

1. Prophylactic effectiveness of live influenza vaccine in 1965;Okuno;Biken's J.,1966

2. TYPING OF Q-PHASE INFLUENZA-A VIRUS BY SERUM-NEUTRALISATION TESTS IN MONKEY-KIDNEY CULTURES

3. Study of the genetic characters of vaccine strains of type A-2 influenza virus;Soloviev;Probl. Virol.,1961

4. Laboratory studies on a strain of Asian influenza virus used as a living vaccine. (A report to the Medical Research Council Committee on Influenza and other Respiratory Virus Vaccines)

5. Comparative study of the immunological properties of live influenza vaccine in volunteers;Ritova;J. Hyg. Epidem. Microbiol. Immun,1963

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