The Clotting of Plasma through Staphylococci and their Products

Author:

Walston H. D.

Abstract

1. Whole cultures, suspensions in distilled water, and cell-free filtrates of Staphylococci clot citrated and other plasmas.2. Whole cultures and filtrates are comparatively thermostable, while suspensions are less so. Partially purified filtrates are likewise less stable than the crude filtrates.3. The clotting principle is precipitable by alcohol, acetic acid, and ammonium sulphate.4. The clotting principle is dialysable through cellophane after alcoholic precipitation but not before.5. The clotting principle is distinct from haemolysin.6. Sera can be obtained which have a neutralising action on the clotting principle.7. Pure fibrinogen can be clotted by a staphylococcal filtrate.8. The clotting principle is distinct from the toxin responsible for local inflammation and fixation.9. The clot formed by the addition of “coagulase” to plasma is composed of true fibrin.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Epidemiology

Cited by 32 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. �ber die Natur der im Epicutantest wirksamen Stoffe von Staphylococcus aureus;Archiv f�r Klinische und Experimentelle Dermatologie;1967

2. Thrombophlebitis and Basic Vascular Problems;Angiology;1967-01

3. Mouse virulence and coagulase production inStaphylococcus aureus;The Journal of Pathology and Bacteriology;1963-07

4. AN INTRODUCTION TO CHAOS, OR THE CLASSIFICATION OF MICROCOCCI AND STAPHYLOCOCCI;Journal of Applied Bacteriology;1962-12

5. PURIFICATION OF STAPHYLOCOCCAL COAGULASE;Journal of Bacteriology;1960-06

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