An antigenic variant of the Hong Kong/68 influenza A 2 virus

Author:

Pereira Marguerite S.,Schild G. C.

Abstract

SUMMARYBoth the haemagglutinin and the neuraminidase of influenza A 2 virus have undergone progressive antigenic drift since this subtype first appeared in 1957.In 1968 a strain showing a much greater antigenic difference was isolated in Hong Kong. This variant has been responsible for epidemics throughout the world in the past 2 years.In the second year of its prevalence a small proportion of strains isolated showed a small but definite antigenic change, related principally to the haemagglutinin component.This new variant formed about 4 % of all strains investigated and was detected in Britain, Portugal, France and New Zealand.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,Immunology

Reference9 articles.

1. Influenza viruses 1957–60;Isaacs;Bulletin of the World Health Organization,1962

2. Preparation and properties of antibody directed specifically against the neuraminidase of influenza virus;Webster;Journal of Immunology,1967

3. Antibody against influenza A2 virus neuraminidase in human sera

4. THE HONG KONG/68 INFLUENZA A2 VARIANT

5. Antigenic variants of influenza A2 virus;Pereira;Bulletin of the World Health Organization,1964

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