A quantitative comparison of the sensitivity of serological tests for bovine brucellosis to different antibody classes

Author:

Allan G. S.,Chappel R. J.,Williamson P.,McNaught D. J.

Abstract

SUMMARYBrucella-specific antibodies of different immunoglobulin classes were quantitatively evaluated with respect to their efficiency in serological tests for bovine brucellosis.IgM reacted more efficiently than IgG1and IgG2in both the Rose Bengal plate test and serum agglutination test. The complement fixation test was found to be slightly more sensitive to IgM than to IgG1and did not react to IgG2.IgM was, however, partly inactivated when heated at 60°C. in the presence of serum.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,Immunology

Reference20 articles.

1. An acidified antigen for detection of non-specific reactions in the plate-agglutination test for bovine brucellosis;Rose;American Journal of Veterinary Research,1957

2. Mechanisms of prozone formation in agglutination reaction

3. Evaluation of a two-channel automated system for the sero-diagnosis of brucellosis

4. The Rose Bengal test

5. Brucellosis in animals: diagnosis and control;Morgan;Proceedings of the Royal Society of Medicine,1969

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