Studies of respiratory viruses in personnel at an Antarctic base

Author:

Holmes M. J.,Allen T. R.,Bradburne A. F.,Stott E. J.

Abstract

SUMMARYThirteen men wintering on an Antarctic base were isolated from other human contact for 10 months. During this period Coxsackievirus A21 and later influenza A2 virus were administered to some of the men. Serum samples were collected from each of the men at monthly intervals.Coxsackievirus A21 produced symptoms and apparently spread to uninoculated men. It also appears that repeated re-infections occurred and that the virus persisted in this small community for most of the period of isolation. HI antibody responses in the absence of neutralizing antibody responses seem to be transient.The vaccine strain of influenza virus induced antibody responses but did not cause symptoms. There was no evidence of spread to uninoculated men.Antibody titres against influenza C, parainfluenzaviruses 1 and 2 and coronavirus OC43 did not fall significantly during isolation.An outbreak of respiratory illness occurred at the end of isolation and its origin was traced. No causative agent was detected.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,Immunology

Reference22 articles.

1. Protective Effect of Antibody to Parainfluenza Type 1 Virus

2. Factors influencing host-virus interactions: III. Further studies on the alteration of Coxsackie virus in adult mice by environmental temperature;Walker;Journal of Immunology,1958

3. Some improved techniques for the study of rhinoviruses using HeLa cells

4. La théorie des germes et ses applications á la médecine et à la chirurgie;Pasteur;Bulletin de l' Académic de Médicine,1878

5. III. Myxoviruses: Parainfluenza

Cited by 38 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Prospective Surveillance of Respiratory Infections in British Antarctic Survey Bases During the COVID-19 Pandemic;The Journal of Infectious Diseases;2022-10-10

2. Index;Life in Extreme Environments;2020-10-15

3. Plate Section (PDF Only);Life in Extreme Environments;2020-10-15

4. Life at the extremes;Life in Extreme Environments;2020-10-15

5. Adaptation/acclimatisation mechanisms of oxyphototrophic microorganisms and their relevance to astrobiology;Life in Extreme Environments;2020-10-15

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3