Author:
Bronne–Shanbury Caroline J.,Miller Delphine,Standfast A. F. B.
Abstract
SUMMARYClassification, by agglutinogens, of 634 isolates ofBordetella pertussiscollected from 1941 to 1968 in Great Britain demonstrated that a change from a predominantly 1,2,0,4 serotype (75% of those examined during 1941–4) to a predominantly 1,0,3,0 serotype (73% of those examined during 1966–8) occurred sometime after 1953. Furthermore, evidence from the examination of isolates collected between 1941 and 1953 suggests that the change may have been gradual. Isolates of serotype 1,2,3,4 made up 20–30% of the total of our cross-country selection for the periods 1941–4, 1946–9, 1950–3 and 1966–8, but over shorter periods in individual areas the percentage varied from negligible to as high as half of those isolated. Results from other countries show a similar drift towards a 1,0,3 serotype but more often from a 1,2,3 than from 1,2,0 serotype.The value, in epidemiological studies, of extended information obtained by monospecific typing sera to all six, rather than only two or three agglutinogens, and confirmation of the results by agglutinin production is demonstrated: for instance not all 1,0,3 isolates were identical.
Publisher
Cambridge University Press (CUP)
Subject
Public Health, Environmental and Occupational Health,Immunology
Reference22 articles.
1. Surveillance of whooping cough in Czechoslovakia. II. Incidence of antigenic types of Bordetella pertussis in Czechoslovakia in years 1966–1970;Maixnerova;Journal of Hygiene, Epidemiology, Microbiology and Immunology,1972
2. Effectiveness of Pertussis Vaccines
3. Andersen E. K. (1966). Private communication to A. F. B. Standfast.
4. The importance of agglutinin production in mice in the determination of the definitive serotype ofBordetella pertussis
5. Type-specific Immunity Against Whooping-cough
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