Natural And Immune Bactericidins For The Gonococcus

Abstract

1. Normal human sera have no natural bactericidins active against strains of gonococci.2. Normal sera from eleven other mammalian species showed a powerful bactericidal action against various strains of gonococci.3. The serological heterogeneity of the gonococcus group revealed by agglutination and complement fixation is again demonstrated in the bactericidal test with immune antiserum.4. There is a steady rise in the incidence of positive bactericidal action in the sera of patients following the progress of infection with the gonococcus.5. The probable significance of these bactericidins, natural and immune, discussed.Acknowledgments. I wish to express my gratitude to Dr Ledingham for the facilities for work granted me at the Lister Institute and to Dr Schiitze for his kind help and critical advice during the progress of this investigation.