Use of a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) strand-specific assay to evaluate for prolonged viral replication >20 days from illness onset-Reference-Cited by-同舟云学术

Use of a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) strand-specific assay to evaluate for prolonged viral replication >20 days from illness onset

Published:2023-06-29 Issue:12 Volume:44 Page:2078-2080
ISSN:0899-823X
Container-title:Infection Control & Hospital Epidemiology
language:en
Short-container-title:Infect. Control Hosp. Epidemiol.

Author:

Ferguson Jessica D.^ORCID,Tayyar Ralph^ORCID,Contreras Gustavo^ORCID,Kiener Melanie^ORCID,Zimmet Alex N.^ORCID,Contag Caitlin A.^ORCID,Rodriguez Nava Guillermo^ORCID,Tompkins Lucy S.^ORCID,Shepard John,Rosenthal Ayelet,Subramanian Aruna K.^ORCID,Pinsky Benjamin A.^ORCID,Salinas Jorge L.^ORCID

Abstract

AbstractSevere acute respiratory coronavirus virus 2 (SARS-CoV-2) real-time reverse-transcription polymerase chain reaction (rRT-PCR) strand-specific assay can be used to identify active SARS-CoV-2 viral replication. We describe the characteristics of 337 hospitalized patients with at least 1 minus-strand SARS-CoV-2 assay performed >20 days after illness onset. This test is a novel tool to identify high-risk hospitalized patients with prolonged SARS-CoV-2 replication.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Microbiology (medical),Epidemiology

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