Abstract
SUMMARYKlebsiella aerogenesstrain V9A carries determinants AKand TK, giving resistance to ampicillin and tetracycline, and a plasmid FKlac, but no active sex factor. F− and I-type sex factors were able to transfer TKfrom V9A toEscherichia coliK12 and between strains of K12, and TKbehaved as a separate plasmid with its own replicon. AKcould not be transferred, except possibly by a sex factor carrying its own A determinant, but the evidence for such transfer was inconclusive. It is suggested that AKis either a chromosomal gene or is in a plasmid with a cell attachment inKlebsiellanot represented inE. coliK12. AKproduces a β-lactamase.
Subject
Genetics,General Medicine
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