Transfer characteristics of two resistance determinants in a wild strain ofKlebsiella aerogenes(V9A)

Author:

Reeve E. C. R.

Abstract

SUMMARYKlebsiella aerogenesstrain V9A carries determinants AKand TK, giving resistance to ampicillin and tetracycline, and a plasmid FKlac, but no active sex factor. F− and I-type sex factors were able to transfer TKfrom V9A toEscherichia coliK12 and between strains of K12, and TKbehaved as a separate plasmid with its own replicon. AKcould not be transferred, except possibly by a sex factor carrying its own A determinant, but the evidence for such transfer was inconclusive. It is suggested that AKis either a chromosomal gene or is in a plasmid with a cell attachment inKlebsiellanot represented inE. coliK12. AKproduces a β-lactamase.

Publisher

Hindawi Limited

Subject

Genetics,General Medicine

Reference8 articles.

1. Acetylornithinase of Escherichia coli: partial purification and some properties;Vogel;Journal of Biological Chemistry,1956

2. Reeve E. C. R. & Braithwaite J. A. (1970). FK lac, an episome with unusual properties found in a wild strain of a Klebsiella species. Nature, Lond. (in the Press).

3. Transduction of linked genetic characters of the host by bacteriophage P1

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