Abstract
An investigation of mitotic segregation and recombination inA. nigergave the following results:1. Thirty-one non-allelic markers have been assigned to six linkage groups (containing 11, 9, 6, 3, 1 and 1 markers respectively) by the analysis of haploid mitotic segregants from synthesized diploids.2. The sequence of nine markers in one linkage group was determined and some of the map intervals were estimated by the analysis of haploids, recombinants for linked markers.3. Almost all the haploid segregants were obtained on medium supplemented with the aminoacid analogue,p-fluoro-phenylalanine, the action of which is interpreted as an induction of chromosome losses.4. The rates of mitotic crossing-over and haploidization are much higher than in the sexual speciesA. nidulansand the data support Pontecorvo's (1958) suggestion that the parasexual cycle can be a substantial alternative to the sexual cycle.
Subject
Genetics,General Medicine
Reference16 articles.
1. Mitotic recombination in the genetic system of filamentous fungi;Pontecorvo;Caryologia,1954
2. Genetic Recombination without Sexual Reproduction in Aspergillus niger
3. The use of p-fluorophenylalanine with ‘master strains’ of Aspergillus nidulans for assigning genes to linkage groups;McCouly;Genet. Res,1965
4. Somatic crossing over and segregation in Drosophila melanogaster;Stern;Genetics,1936
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