Characterization of a new choline locus inAspergillus nidulansand its significance for choline metabolism

Abstract

SUMMARYA new locus for choline-requirement has been identified inAspergillus nidulansand designatedchoC3. It has been located to linkage group VIII at a position 31·9 ± 2·2 map units to the left of thesDlocus.It is proposed that this locus codes either for the enzyme that catalyses the transmethylation of phosphatidyl monomethylaminoethanol to phosphatidyl dimethylaminoethanol or for a molecule essential for the synthesis or function of this enzyme.