Effect of testing methods on incidence of Clostridioides difficile infection rates in Veterans’ Affairs medical centers

Author:

McCauley Brian P.ORCID,Evans Martin E.,Simbartl Loretta A.,Gamage Shantini D.,Kralovic Stephen M.,Roselle Gary A.

Abstract

AbstractClostridioidesdifficile infection rates from 7 facilities that used nucleic acid amplification testing (NAAT) alone for 12 months then switched to NAAT plus toxin enzyme immunoassay (EIA) and reported the latter result for 12 months were compared to 70 facilities that used NAAT alone for all 24 months. There was no significant difference in rates between facility groups over the first 12 months (P = .21, linear regression), but we detected a decrease in rates for the facilities that changed to NAAT+EIA (P < .0001).

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Microbiology (medical),Epidemiology

Reference9 articles.

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4. Performance of Clostridium difficile toxin enzyme immunoassay and nucleic acid amplification tests stratified by patient disease severity;Humphries;J Clin Microbiol,2013

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