Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Author:

Jamal Alainna J.ORCID,Mozafarihashjin Mohammad,Coomes Eric,Anceva-Sami Sofia,Barati Shiva,Crowl Gloria,Faheem Amna,Farooqi Lubna,Kandel Christopher E.,Khan Saman,Li Angel X.,Mistry Henna,Paterson Aimee,Plenderleith Simon,Prost Karren,Poutanen Susan,Powis Jeff,Schryer Renée,Taylor Maureen,Yip Lily,Zhong Xi Zoe,McGeer Allison J.,Mubareka Samira,

Abstract

AbstractTo compare sensitivity of specimens for COVID-19 diagnosis, we tested 151 nasopharyngeal/midturbinate swab pairs from 117 COVID-19 inpatients using reverse-transcriptase polymerase chain reaction (RT-PCR). Sensitivity was 94% for nasopharyngeal and 75% for midturbinate swabs (P = .0001). In 88 nasopharyngeal/midturbinate pairs with matched saliva, sensitivity was 86% for nasopharyngeal swabs and 88% for combined midturbinate swabs/saliva.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Microbiology (medical),Epidemiology

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