Ricerche sulla ereditarietà dell'idroftalmo e della cataratta congenita in paesi delle Prealpi Orobiche

Abstract

SUMMARYFrom the whole of genealogical researches on the people of B., P. and Al. towns, we came to the following conclusions:1) the monomeric recessive autosomal transmission of hydrophtalmos, with a high degree of penetration, has been confirmed;2) a type of congenital cataract with monomeric recessive autosomal hereditary transmission, with a comparatively reduced degree of penetration, has been located;3) in towns B. and P. affected lines of hydrophtalmos and congenital cataract have been located;4) the first definite heterozygotes for hydrophtalmos in town B. and for hydrophtalmos and congenital cataract in town P. have been located: they date back to the first half of the 18th Century;5) the date of hydiovariation's inception has been located at about two or three generations before, or around the middle of the 17th Century.