Author:
Deslauriers Roxanne,Geoffrion Yves,Butler Keith W.,Smith Ian C. P.
Abstract
The non-invasive and non-destructive aspects of NMR and ESR spectroscopy have prompted a variety of research on the pathophysiological impact of murine malaria. NMR is unique in its ability to monitor intracellular pH non-invasively in a heterogeneous sample, a compartmentalized cell and in a whole organism. It has also been shown to be sensitive to unusual structures and metabolic products in free-living protozoa such asAcanthamoeba(Deslaurierset al.1982a) andTetrahymena(Deslaurierset al.1982b; Jarrellet al.1981). Using the appropriate spin probe, ESR can give valuable information on membrane structure (Schreier, Polnaszek & Smith; 1978). It is particularly useful when quantities of material are limited.
Publisher
Cambridge University Press (CUP)
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