Drug and Natural Health Product Data Collection and Curation in the Canadian Longitudinal Study on Aging
-
Published:2024-01-25
Issue:
Volume:
Page:1-7
-
ISSN:0714-9808
-
Container-title:Canadian Journal on Aging / La Revue canadienne du vieillissement
-
language:en
-
Short-container-title:Can. J. Aging
Author:
Cossette Benoit,Griffith Lauren,Emond Patrick D.,Mangin Dee,Moss Lorraine,Boyko Jennifer,Nicholson Kathryn,Ma Jinhui,Raina Parminder,Wolfson Christina,Kirkland Susan,Dolovich Lisa
Abstract
Abstract
This study aimed to develop an efficient data collection and curation process for all drugs and natural health products (NHPs) used by participants to the Canadian Longitudinal Study on Aging (CLSA). The three-step sequential process consisted of (a) mapping drug inputs collected through the CLSA to the Health Canada Drug Product Database (DPD), (b) algorithm recoding of unmapped drug and NHP inputs, and (c) manual recoding of unmapped drug and NHP inputs. Among the 30,097 CLSA comprehensive cohort participants, 26,000 (86.4%) were using a drug or an NHP with a mean of 5.3 (SD 3.8) inputs per participant user for a total of 137,366 inputs. Of those inputs, 70,177 (51.1%) were mapped to the Health Canada DPD, 20,729 (15.1%) were recoded by algorithms, and 44,108 (32.1%) were manually recoded. The Direct algorithm correctly classified 99.4 per cent of drug inputs and 99.5 per cent of NHP inputs. We developed an efficient three-step process for drug and NHP data collection and curation for use in a longitudinal cohort.
Funder
Institute of Aging
Canada Foundation for Innovation
Publisher
Cambridge University Press (CUP)
Subject
Geriatrics and Gerontology,Community and Home Care,Gerontology,Health (social science)
Reference24 articles.
1. OCRx: Canadian Drug Ontology;Nikiema;Studies in Health Technology and Informatics,2021
2. Automated mapping of pharmacy orders from two electronic health record systems to RxNorm within the STRIDE clinical data warehouse;Hernandez;AMIA … Annual Symposium Proceedings. AMIA Symposium,2009
3. An Introduction to Health Care Administrative Data;Cadarette;The Canadian Journal of Hospital Pharmacy,2015
4. Recommendations for reporting randomized controlled trials of herbal interventions: Explanation and elaboration;Gagnier;Journal of Clinical Epidemiology,2006
5. The inevitable application of big data to health care;Murdoch;JAMA,2013