Is sudden cardiac death predictable in LEOPARD syndrome?-Reference-Cited by-同舟云学术

Is sudden cardiac death predictable in LEOPARD syndrome?

Published:2006-11-20 Issue:6 Volume:16 Page:599-601
ISSN:1047-9511
Container-title:Cardiology in the Young
language:en
Short-container-title:Cardiol Young

Author:

Limongelli Giuseppe,Pacileo Giuseppe,Calabrò Raffaele

Abstract

We report the sudden cardiac death of a young male presenting with classic clinical features of LEOPARD syndrome, shown to be due to a mutation in the PTPN11 gene, and severe non obstructive hypertrophic cardiomyopathy. We also discuss briefly the usefulness of prophylactic risk stratification in patients with syndromic and non syndromic hypertrophic cardiomyopathy.

Publisher

Cambridge University Press (CUP)

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Pediatrics, Perinatology, and Child Health

Reference10 articles.

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2. Woywodt A , Welzel J , Haase H , et al. Cardiomyopathic Lentiginosis/LEOPARD syndrome presenting as sudden cardiac arrest. Chest 1998; 113: 1415–1417.

3. Gorlin RJ , Anderson RC , Blaw M . Multiple lentigines syndrome. Am J Dis Child 1969; 117: 652–662.

4. Mogensen J , Bahl A , McKenna WJ . Hypertrophic cardiomyo-pathy-the clinical challenge of managing an hereditary heart condition. Eur Heart J 2003; 24: 496–498.

5. Digilio MC , Sarkozy A , Pacileo G , Limongelli G , Marino B , Dallapiccola B . PTPN11 gene mutations: linking the Gln510Glu mutation to the “LEOPARD syndrome phenotype”. Eur J Pediatr 2006; DOI 10.1007/s00431-006-0163-7.

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