Author:
Beckman Robert A.,Loeb Lawrence A.
Abstract
The mechanisms by which DNA polymerases achieve their remarkable fidelity, including base selection and proofreading, are briefly reviewed. Nine proofreading models from the current literature are evaluated in the light of steady-state and transient kinetic studies ofE. coliDNA polymerase I, the beststudied DNA polymerase.
Publisher
Cambridge University Press (CUP)
Cited by
50 articles.
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