Abstract
AbstractIt is widely recognized that dizygotic twinning (DZT) runs in families, but estimates of heritability from twin and family data are remarkably scarce and vary considerably. Here, we traced seven large, sometimes historical, multigeneration pedigrees from West Africans, fin de siècle French Jews, Canadians (two pedigrees), and the French royal family, in which twin births were recorded. We estimated heritability of twinning (of all types) as zygosity information was not available, diluting the true DZT heritability by a third or so. The estimates in the range 8−20% are remarkably consistent across time (8−19 generations) and ethnicities and also consistent with twin and family estimates.
Publisher
Cambridge University Press (CUP)
Subject
Genetics (clinical),Obstetrics and Gynecology,Pediatrics, Perinatology and Child Health
Reference19 articles.
1. Frequency of Twin Births in Developed Countries
2. Zur Bedeutung der Mehrlingsgeburten für die Frage der Bestimmung des Geschlechts;Weinberg;Arch Rass Gesellschaftsbiol,1909
3. Bayesian Inference with INLA
4. Genetic contribution to DZ twinning
5. Multiple births: trends and patterns in Canada, 1974–1990;Millar;Health Reports,1992
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