Author:
Wilcox Duncan T,Karamanoukian Hratch L,Glick Philip L
Abstract
Congenital diaphragmatic hernia (CDH) is a simple anatomical defect. The reported incidence is between 1:2000 and 1:5000 live births, with the majority affecting the left side. A defect in the diaphragm allows abdominal viscera to herniate into and stay within the thoracic cavity during crucial stages of lung development. This results in pulmonary hypoplasia, a reduction in pulmonary vascular branching and an alteration in the surfactant system.
Publisher
Cambridge University Press (CUP)
Subject
Obstetrics and Gynaecology,Pediatrics, Perinatology, and Child Health
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