Author:
TAPERT SUSAN F.,GRANHOLM ERIC,LEEDY NATHAN G.,BROWN SANDRA A.
Abstract
This study prospectively examined neuropsychological (NP)
functioning associated with adolescent substance use and
withdrawal. Participants were youths with histories of substance
use disorders (n = 47) and demographically comparable
youths with no such lifetime histories (n = 26). They
were followed with NP testing and substance involvement interviews
at 7 time points spanning 8 years, from ages 16 to 24, on average.
After controlling for recent use, age, education, practice effects,
and baseline NP functioning, substance use over the 8-year
follow-up period significantly predicted performances on tests
of memory and attention at Year 8. Additionally, withdrawal
symptoms during the follow-up predicted visuospatial and attention
scores at Year 8. Findings suggest that use and withdrawal may
differentially impact neurocognitive functioning during youth,
with heavy use leading to learning, retention, and attentional
difficulties, and withdrawal leading to problems with visuospatial
functioning. (JINS, 2002, 8, 873–883.)
Publisher
Cambridge University Press (CUP)
Subject
Psychiatry and Mental health,Clinical Neurology,Clinical Psychology,General Neuroscience
Cited by
216 articles.
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