Author:
LACRITZ LAURA H.,JR. RICHARD DEWEY,GILLER, COLE,CULLUM C. MUNRO
Abstract
Essential tremor (ET) is the most common type of movement
disorder, although its etiology and neurophysiological substrates
remain unclear. While thought to be a benign condition, it has
yet to be studied from a neuropsychological perspective. We
examined the neurocognitive functioning of 13 nondemented subjects
with severe ET, including aspects of memory, cognitive flexibility,
and attention. Results revealed that 12/13 subjects
demonstrated impairment on 1 or more cognitive measures in
comparison with published normative data. The pattern of findings
was suggestive of relative dysfunction of frontal-mediated
processes not unlike that seen in Parkinson's disease.
These deficits were found in subjects irrespective of the presence
of cognitive complaints, depression, or the existence of other
potential neurocognitive risk factors. These findings suggest
that mild cognitive deficits are not uncommon in association
with severe ET and may be related to subcortical systems.
(JINS, 2002, 8, 125–129.)
Publisher
Cambridge University Press (CUP)
Subject
Psychiatry and Mental health,Clinical Neurology,Clinical Psychology,General Neuroscience
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