Author:
HU H. Y.,WU C. Y.,HUANG N.,CHOU Y. J.,CHANG Y. C.,CHU D.
Abstract
SUMMARYThis nationwide population-based cohort study investigated the risk of tuberculosis (TB) in patients with end-stage renal disease (ESRD) and receiving dialysis. The evaluations included 4131 incident ESRD patients receiving dialysis and 16 524 age- and gender-matched controls, recruited between 1998 and 2009. We used Cox proportional hazards regression analysis to measure the association between TB and ESRD. Compared to the controls, the ESRD cohort had a significantly higher risk of TB within 1 year [incident rate ratio (IRR) 4·13], and 1–2 years (IRR 2·12), of occurrence of ESRD. The Cox proportional hazards model revealed that ESRD [hazard ratio (HR) 2·40], age >65 years (HR 2·41), male sex (HR 1·94), diabetes mellitus (HR 1·36), silicosis (HR 7·70) and chronic obstructive pulmonary disease (HR 1·61) are independent risk factors for TB. Patients with ESRD are associated with an increased risk of TB, and should thus be monitored more carefully for TB, especially within 2 years of onset of ESRD.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Epidemiology
Reference22 articles.
1. Tuberculous spondylitis in patients with end-stage renal disease undergoing chronic haemodialysis therapy – report of two cases;Kostov;Central European Journal of Medicine,2010
2. Association between Tobacco Smoking and Active Tuberculosis in Taiwan
3. Mycobacterium tuberculosis infection of end-stage renal disease patients in Taiwan: a nationwide longitudinal study
4. World Health Organization. WHO Report. Global tuberculosis control. Geneva, Switzerland: WHO, 2010 (http://www.who.int/mediacentre/factsheets/fs104/en/index.html). Accesed 17 September 2012.
5. Risk Factors for Tuberculosis in HIV-lnfected Persons
Cited by
27 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献