Author:
PICHEL M.,GONZÁLEZ FRAGA S.,TERRAGNO R.,MULKI J.,GENTILE A.,KREMER C.,MOLA A. M.,NOSEDA R.,BINSZTEIN N.
Abstract
SUMMARYThirty-five isolates ofShigella sonneifrom patients with diarrhoea in three geographic regions of Argentina were examined for genetic diversity by pulsed-field gel electrophoresis (PFGE) and plasmid profile. PFGE ofXbaI andBlnI DNA digests confirmed the occurrence of outbreaks in two regions caused by two separate predominant clones ofS. sonnei. The third region was characterized by three circulating clones, one of which was possibly associated with an outbreak. Similar plasmids were found in distinct clones and in one outbreak clone five different plasmid profiles were identified. Antimicrobial resistance of the isolates varied from fully susceptible to the agents tested, to resistance to cotrimoxazole, ampicillin and ciprofloxacin. Antibiotic resistance did not correlate with plasmid content. This information will form the basis for active surveillance of shigellosis in Argentina and elsewhere in the region through the PulseNet International Network.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Epidemiology
Reference23 articles.
1. Outbreak of Shigella sonnei in a rural hotel in La Gomera, Canary Islands, Spain;Alcoba;International Microbiology,2005
2. Antimicrobial Resistance and Genetic Diversity of
Shigella sonnei
Isolates from Western Ireland, an Area of Low Incidence of Infection
3. Enzyme polymorphism and genetic population structure in Escherichia coli and Shigella;Ochman;Journal of General Microbiology,1983
4. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing;Tenover;Journal of Clinical Microbiology,1995
Cited by
13 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献