Author:
Cilla G.,García-Bengoechea M.,Trallero E. Perez,Montalvo I.,Vicente D.,Arenas J. I.
Abstract
SummaryThe genotype of HCV was determined in 161 chronic HCV-infected patients. The patients were classified into three groups on the basis of the origin of the HCV infection: 50 patients had a history of intravenous drug use (IVDU) but no HIV infection; 41 patients had received blood transfusions, and 70 patients had no known exposure. The distribution of HCV genotypes was associated with the origin of infection and age of patients: genotype 1b was predominant among patients who had received blood transfusions and those without evidence of parenteral exposure (84·6% and 67·7%, respectively), whereas genotype 3a was present in 65·3% of IVDUs. Patients with genotype 1b were older than those with genotypes la or 3a: 50·3 ± 12 vs. 34·1±9·9 and 31 ± 5.4 years, respectively. These findings suggest that the pattern of HCV genotypes in our region is changing and that genotype 1b may be substituted by 3a as the dominant genotype in the future.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Epidemiology
Reference29 articles.
1. Hepatitis posttransfusional en Navarra. Evidencia de infección aguda por el virus de la hepatitis C sin elevación de aminotransferasas;Huarte;Med Clin (Barc.),1994
2. Hepatitis posttransfusional después de cirugía cardíca: incidencia clínica y pronóstico;Barrera;Med Clin (Barc.),1987
3. Prevalence of hepatitis C virus genotypes in Italy;Pistello;J Clin Microbiol,1994
4. A new type of hepatitis C virus in patients in Thailand
5. Prevalence and Determinants of Anti-HCV Seropositivity and of HCV Genotype among Intravenous Drug Users in Berlin
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献