Epidemiology ofPseudomonas aeruginosakeratitis in contact lens wearers

Abstract

SUMMARYThis study evaluated the epidemiology ofPseudomonas aeruginosakeratitis in contact lens (CL) wearers; the relationships between CL storage case contamination and CL hygiene practice and between CL hygiene and the development of keratitis. Sixteen CL wearers with keratitis were compared with 44 asymptomatic controls. Lens hygiene practice was assessed and CL care materials, domestic water sites and endogenous sites were evaluated microbiologically. Poor CL hygiene was not associated withPs. aeruginosakeratitis. There was an association between keratitis and bacterial contamination of the CL and storage case (P < 0·0005). Lens and storage case contamination were not significantly associated with poor hygiene. No domestic or endogenous source forPs. aeruginosawas found. Causative organisms may be derived from other sources, but CLs and CL storage cases provide a favourable environment forPs. aeruginosacolonization. Changing the CL care environment to one less favourable forPs. aeruginosamay help to eliminate this problem.