Author:
CILLA G.,PÉREZ-TRALLERO E.,LÓPEZ-LOPATEGUI M. C.,GILSETAS A.,GOMÁRIZ M.
Abstract
Over a 14-year period (1984–97) the presence of rotavirus in stool samples from children under
15 years with acute gastroenteritis was studied by enzymoimmunoanalysis. Serotyping (G1–G4)
was performed using monoclonal antibodies. A total of 17348 children under 15 were
investigated. Rotavirus was detected in 3637 (21·0%) specimens, 74·6% of which were from
children younger than 2 years old. G1 and G4 were the most frequent serotypes. In 1991–7,
the minimum incidence of rotavirus gastroenteritis in children under 4 years of age was 21·7
cases/1000 children/year. By the age of 5 years, at least 1 out of 11·3 children and probably 1
out of every 5–6 children in this area had experienced an episode of rotavirus gastroenteritis
that required medical care. In the 1984–90 period a clear seasonality was not observed but in
the second period of the study (1991–7), seasonality was marked, with peak activity in winter.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Epidemiology
Cited by
37 articles.
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