Control of the fetoplacental circulation

Author:

Macara Lena M,Kingdom John CP,Kaufmann Peter

Abstract

This year marks the 250th anniversary of the discovery by William Hunter of the existence of two distinct circulations within the human placenta. Until relatively recently the placenta has been viewed with “respect” – a passive structure which occasionally elicited fear and anxiety if implanted either too low or too deep. More recently our understanding of perinatal physiology, blood flow regulation and epidemiological data linking prenatal events with adult disease has created renewed interest in the placenta. This review will focus on the regulation of fetal blood flow in the placenta, the possible mechanisms whereby it may be deranged and why this might be relevant to adult disease.

Publisher

Cambridge University Press (CUP)

Subject

Obstetrics and Gynecology,Pediatrics, Perinatology and Child Health

Cited by 30 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Fetal Vascular Malperfusion;Benirschke's Pathology of the Human Placenta;2021-12-08

2. Basic Structure of a Placental Villus;Benirschke's Pathology of the Human Placenta;2021-12-08

3. Anatomy and Pathology of the Umbilical Cord;Benirschke's Pathology of the Human Placenta;2021-12-08

4. Structural and Functional Developmental Perspectives of the Placental Barrier and Its Role in the Fetal Development During the First and Second Trimesters;Human Fetal Growth and Development;2016

5. The use of Doppler evaluation of the canine umbilical artery in prediction of delivery time and fetal distress;Animal Reproduction Science;2015-03

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