ASPIRIN ADMINISTRATION FOR PREVENTION OF ADVERSE PREGNANCY OUTCOMES

Author:

BUJOLD EMMANUEL,ROBERGE STÉPHANIE,DEMERS SUZANNE,NICOLAIDES KYPROS H

Abstract

The prophylactic use of low-dose aspirin for prevention of preeclampsia has been an important research question in obstetrics for the last three decades. In 1979, Crandon and Isherwood observed that nulliparous women who had taken aspirin regularly during pregnancy were less likely to have preeclampsia than women who did not. In 1985, Beaufils et al published the first randomized trial suggesting that 150 mg aspirin and 300 mg dipyridamole daily from 3 months’ gestation onwards decreased the risk of preeclampsia, fetal growth restriction and stillbirth in high-risk women. Subsequently, more than 50 trials have been carried out throughout the world and a meta-analysis of these studies reported that the administration of low-dose aspirin in high-risk pregnancies is associated with a decrease in the rate of preeclampsia by approximately 10%. Consequently, several national professional bodies recommend that high-risk pregnancies should be treated with aspirin (50–150 mg daily).

Publisher

Cambridge University Press (CUP)

Subject

Obstetrics and Gynecology,Pediatrics, Perinatology and Child Health

Reference87 articles.

1. Aspirin (100 mg) used for prevention of pre-eclampsia in nulliparous women: The essai regional aspirine mere-enfant study (part 1);Subtil;BJOG,2003

2. National Collaborating Centre for Women's and Children's Health. Commissioned by the national institute for health and clinical excellence. Hypertension in pregnancy: The management of hypertensive disorders during pregnancy. Cg107. 2011.

3. The Relation of Aspirin Use during the First Trimester of Pregnancy to Congenital Cardiac Defects

4. Low-dose aspirin: Lack of association with an increase in abruptio placentae or perinatal mortality

5. Is pre-eclampsia more than one disease?

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3