Verbal working memory in HIV-seropositive drug users

Author:

FARINPOUR ROXANNA,MARTIN EILEEN M.,SEIDENBERG MICHAEL,PITRAK DAVID L.,PURSELL KENNETH J.,MULLANE KATHLEEN M.,NOVAK RICHARD M.,HARROW MARTIN

Abstract

Recent evidence suggests that HIV-seropositive drug users are impaired on tasks of visuospatial working memory compared with drug users seronegative for HIV. In the current study we evaluated the performance of 30 HIV-seropositive male drug users and 30 risk-matched seronegative controls on two measures of verbal working memory, the Listening Span and the verbal Self Ordered Pointing Task. Impaired working memory performance was significantly more common among HIV-seropositive persons compared to controls, with the highest incidence of deficit among symptomatic participants. These findings indicate that working memory deficits in persons with HIV are not domain-specific and can be demonstrated reliably in drug users. (JINS, 2000, 6, 548–555.)

Publisher

Cambridge University Press (CUP)

Subject

Psychiatry and Mental health,Clinical Neurology,Clinical Psychology,General Neuroscience

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