Author:
KRAMER JOEL H.,SCHUFF NORBERT,REED BRUCE R.,MUNGAS DAN,DU AN-TAO,ROSEN HOWARD J.,JAGUST WILLIAM J.,MILLER BRUCE L.,WEINER MICHAEL W.,CHUI HELENA C.
Abstract
This study tested the hypothesis that the hippocampus has a
relatively specific role in retaining information over delays.
Thirty-seven subjects with probable Alzheimer's disease were
evaluated with a verbal memory task and structural MRI. Cortical gray
matter but not hippocampal volume predicted immediate free recall. In
contrast, hippocampal volume was the best predictor of how well
information was retained over a delay, even after controlling for
levels of immediate recall. Results suggest that the role of the
hippocampus is relatively specific to the consolidation of new
memories. (JINS, 2004, 10, 639–643.)
Publisher
Cambridge University Press (CUP)
Subject
Psychiatry and Mental health,Clinical Neurology,Clinical Psychology,General Neuroscience
Cited by
70 articles.
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