Author:
Oxlund H.,Pedersen U.,Danielsen C. C.,Oxlund I.,Elbrønd O.
Abstract
AbstractIt has been suggested that otosclerosis might be caused by a generalized disorder in the connective tissue.The biophysical and biochemical properties of skin biopsies from twelve patients with otosclerosis and twelve age- and sex-matched controls were investigated. No differences were found in skin strength and extensibility, skin thickness, collagen content, the relationship between collagen type I and type III, reducible collagen cross-links and molecular stability of collagen type I of samples from patients with otosclerosis as compared with those from the controls. The present study does not support the suggestion that otosclerosis might be a generalized connective tissue disorder.
Publisher
Cambridge University Press (CUP)
Subject
Otorhinolaryngology,General Medicine
Cited by
4 articles.
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