The Use of Microsatellites in Zygosity Diagnosis of Twins

Author:

Erdmann J.,Nöthen M.M.,Stratmann M.,Fimmers R.,Franzek E.,Propping P.

Abstract

AbstractAlthough numerous genetic and anthropological markers are available for determining zygosity of twins, there is still a need for a more practical and informative method in zygosity diagnosis. Dinucleotide repeats or other short repeats (microsatellites) are highly variable between individuals and offer a simple, fast, cheap, and exact approach for zygosity determination. The feasibility of a set of microsatellites to be used for this purpose is demonstrated.

Publisher

Cambridge University Press (CUP)

Subject

Genetics (clinical)

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