Genes within the major histocompatibility complex of the guinea pig influence susceptibility to Trichostrongylus colubriformis infection-Reference-Cited by-同舟云学术

Genes within the major histocompatibility complex of the guinea pig influence susceptibility to Trichostrongylus colubriformis infection

Published:1981-04 Issue:2 Volume:82 Page:281-286
ISSN:0031-1820
Container-title:Parasitology
language:en
Short-container-title:Parasitology

Author:

Geczy A. F.,Rothwell T. L. W.

Abstract

SUMMARYThe influence of genes in the major histocompatibility complex (MHC) of the guinea pig on the susceptibility to infection with the parasitic nematode Trichostrongylus colubriformis was investigated. Back-cross analysis of 2 lines of guinea pigs suggests that genes that map in or near the I region of the guinea pig MHC influence susceptibility to infection by the parasite. However, other genes, possibily not linked to the guinea pig MHC, may also be required for the full expression of susceptibility.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Animal Science and Zoology,Parasitology

Reference19 articles.

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4. The guinea pig I region. II. Functional analysis.

5. Vaccination against the nematode Trichostrongylus colubriformis—I. Vaccination of guinea-pigs with worm homogenates and soluble products released during in vitro maintenance

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