Possible immunological damage to the tegument ofHymenolepis diminutain mice and rats

Author:

Befus A. D.,Threadgold L. T.

Abstract

Opaque or darkened areas (DA) of variable size and position occur onHymenolepis diminutain mice and rats. In mice DA normally first appear in the neck region of the worm but subsequently they appear elsewhere and increase in number until destrobilation or worm expulsion. The posterior of destrobilated worms is often darkened. In the more immunogenic infections with six cysticercoids there are more DA per worm than in infections with one cysticercoid. DA are areas of the tegument with a homogeneous increase in electron density; abnormal mitochondria; reduced granular endoplasmic reticulum, Golgi complexes and discoidal secretory bodies; and accumulation of lipid droplets. DA disappear from worms maintained for up to 4 h in Hanks' balanced salt solution and can be induced by mechanical damage to the worms.As the numbers of DA increase with the duration and intensity of infection and have similarities with types of cell injury, they are probably sites of worm pathology induced by host immunity.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Animal Science and Zoology,Parasitology

Reference37 articles.

1. Oxyclozanide (3,3',5,5',6-pentachloro-2,2'-dihydroxybenzanilide--6Zanil") in the treatment of the liver fluke Fasciola hepatica in sheep and cattle

2. Turton J. A. (1968). The growth and development of Hymenolepis diminuta and H. nana in vitro and in vivo. Ph.D. thesis, University of Glasgow, Scotland.

3. Hymenolepis diminuta: Ultrastructure of a unique membrane specialization in tegument

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