The supply of glucose to the brain and cognitive functioning

Author:

Benton David,Parker Pearl Y.,Donohoe Rachael T.

Abstract

Unlike other organs the energy requirement of the brain is met almost exclusively by aerobic glucose degradation (Siesjo, 1978). The energy requirement of the brain is 20–30% of the whole organism at rest, although its weight is only 2%. The energy stores in the brain are extremely small when compared with the high rate of glucose utilisation: thus the brain is reliant on a continuous glucose supply. Only about 30% of glucose is required for direct energy production; much of the remainder is used for the synthesis of amino acids, peptides, lipids and nucleic acids (Siebert, Gessner & Klasser, 1986). Thus a source of glucose is essential for the synthesis of physiologically active amines such as serotonin, noradrenaline and acetylcholine. Although it is well accepted that hypoglycaemia can result in the disruption of cognitive functioning, this is a rare phenomenon and it has usually been assumed that levels of blood glucose, within the normal range, do not influence intellectual functioning. This assumption is discussed in this paper.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,General Social Sciences

Reference84 articles.

1. Energy supply of the central nervous System;Siebert;Bibliotheca Nutritio Dieta,1986

2. Memory improvement by glucose, fructose, and two glucose analogs: A possible effect on peripheral glucose transport

3. From memory span and mental speed toward the quantum mechanics of intelligence

4. EinfluB von dextrose auf fahrleistung, konzentrationsfahigkeit, kreislauf und stoffwechsel im kraftfahrzeug-simulator (Doppelblindstudie im cross-over-design);Keul;Aktuelle Ernaehrungsmedizin,1982

Cited by 79 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3