Effects of an attachment-based intervention on daily cortisol moderated by dopamine receptor D4: A randomized control trial on 1- to 3-year-olds screened for externalizing behavior

Author:

Bakermans-Kranenburg Marian J.,Van IJzendoorn Marinus H.,Mesman Judi,Alink Lenneke R. A.,Juffer Femmie

Abstract

AbstractThe effect of the Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) on daily cortisol production was tested in a randomized controlled trial with 130 families with 1- to 3-year-old children screened for their relatively high levels of externalizing behavior. Six 1.5-hr intervention sessions focusing on maternal sensitivity and discipline were conducted with individual families at their homes. Children in the intervention group showed lower cortisol levels, with a moderating role of the dopamine receptor D4 (DRD4) VNTR exon III polymorphism. The VIPP-SD program proved to be effective in decreasing daily cortisol production in childrenwiththeDRD47-repeat allele, but not in childrenwithouttheDRD47-repeat allele. Our findings indicate that children are differentially susceptible to intervention effects dependent on the presence of the 7-repeatDRD4allele.

Publisher

Cambridge University Press (CUP)

Subject

Psychiatry and Mental health,Developmental and Educational Psychology

Reference84 articles.

1. The New Look of Behavioral Genetics in Developmental Psychopathology: Gene-Environment Interplay in Antisocial Behaviors.

2. Kohnstamm G. A. (1984). Bates' Infant Characteristics Questionnaire (ICQ) in The Netherlands. Paper presented at the fourth biennial International Conference on Infant Studies, New York.

3. Polydrug-using adolescent mothers and their infants receiving early intervention;Field;Adolescence,1998

4. Stress responses of adolescents as a function of anger status and its concomittants;Wright;Dissertation Abstracts International,2000

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