Author:
Lentjes Marjolein HFM,Niessen Hanneke EC,Akiyama Yoshimitsu,de Bruïne Adriaan P,Melotte Veerle,van Engeland Manon
Abstract
The GATA family of transcription factors consists of six proteins (GATA1-6) which are involved in a variety of physiological and pathological processes. GATA1/2/3 are required for differentiation of mesoderm and ectoderm-derived tissues, including the haematopoietic and central nervous system. GATA4/5/6 are implicated in development and differentiation of endoderm- and mesoderm-derived tissues such as induction of differentiation of embryonic stem cells, cardiovascular embryogenesis and guidance of epithelial cell differentiation in the adult.
Publisher
Cambridge University Press (CUP)
Subject
Molecular Biology,Molecular Medicine
Cited by
184 articles.
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