The incidence of natural Clostridium welchii α-antitoxin in Indian equines: its influence on the results of antigenic stimulus

Abstract

Presence of natural Cl. welchii α-antitoxin in 65 Indian equines was observed. All the 65 equines had 1 unit or more of circulating natural antitoxin per ml. of serum. The maximum titre observed was 4 units/ml. in about 8% of the animals. These figures are very much higher than the figures obtained in other countries. Such a high incidence of natural immunity indicates frequent natural contact with the antigen concerned.Results of hyperimmunization of 7 equines are recorded and discussed.Our thanks are due to the authorities of Bengal Immunity Laboratory for permission to publish these observations and to Sri M. Pal for useful technical assistance.