Statistical analysis of data bearing on the number of particles required to form a plaque

Author:

Kalbfleisch J. G.,Sprott D. A.

Abstract

SUMMARYMethods of statistical analysis are presented for one or more dilution series experiments where the quantity of interest is the number of virus particles required to infect a cell. These methods are illustrated on several data sets drawn from the literature. Data from seven series, which have been used to support a two-particle model in the literature, are here shown to reject such a model decisively, whereas fifteen other experiments are found to be in excellent agreement with a one-particle model.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,Immunology

Reference13 articles.

1. A study of fowl pox virus detection on the chorioallantois by the poch counting technique;Reid;Journal of Immunology,1949

2. L'etude par la methode des plaques du virus aphteux (type C) en couche monocellulaire de rein de porcelet;Khera;Annales de l'institut Pasteur,1958

3. Production of Plaques in Monolayer Tissue Cultures by Single Particles of an Animal Virus

4. A study of adenovirus-host cell system by the plaque technique

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