The virulence of strains of poliovirus for cynomolgus monkeys after subcutaneous injection

Author:

Coid C. R.,Beswick T. S. L.,Tobin J. O'H.

Abstract

The virulence of strains of the three types of poliovirus have been examined by the subcutaneous injection of monkeys. The strains used were the Sabin attenuated Types 1, 2 and 3, Cox attenuated Types 1, 2 and 3, the Brunenders Type 1 partially attenuated strain, MEF-1, Type 2 and Saukett, Type 3.The results obtained indicated that the subcutaneous route of injection offers a promising method for comparing and characterizing strains of poliovirus.

Publisher

Cambridge University Press (CUP)

Subject

Infectious Diseases,Epidemiology

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2. Brunenders: a partially attenuated historic poliovirus type I vaccine strain;Journal of General Virology;2015-09-01

3. Containment of Polioviruses After Eradication and OPV Cessation: Characterizing Risks to Improve Management;Risk Analysis;2006-12

4. Zur Neurovirulenzpr�fung von Poliomyelitis-Lebendimpfstoffen;Archiv f�r Psychiatrie und Nervenkrankheiten Vereinigt mit Zeitschrift f�r die Gesamte Neurologie und Psychiatrie;1965

5. The behaviour of attenuated strains of poliovirus in monkeys;Journal of Neurology, Neurosurgery & Psychiatry;1964-02-01

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