The pathogenicity for mice of group B streptococci of bovine origin

Abstract

The following conclusions were drawn from these experiments with bovine group B streptococci:1. A relationship existed between lethal power and the number of living organisms inoculated, and, therefore, the number of living organisms inoculated must be determined when the killing power of a strain is under investigation.2. Equal doses of the same strain were likely to kill more mice, but less rapidly, when inoculated intravenously than when inoculated intraperitone-ally.3. Virulence for mice might be related to serological type.4. The disease caused by intraperitoneal inoculation of strain S 13 was a rapidly fatal peritonitis with concomitant bacteraemia.5. The disease caused by intravenous inoculation of strain S13 was a fatal bacteraemia with a tendency for the streptococci to form dense clumps in widely separated tissues.